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[25] Depending on the time scales over which it acts synaptic enhancement is classified as neural facilitation, synaptic augmentation or post-tetanic potentiation

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the fabricated patch of the transdermal delivery system containing from around 0.5 mg to 200 mg of GHK-Cu per patch intended for a 12 hrs / 24 hrs / 48 hrs /72 hrs delivery aims to provide GHK-Cu in controlled manner to provide additional 120-140 microgram/litre of GHK-Cu to obtain the drug plasma level up to 200 microgram/litre

The barrier integrity of the model was verified by permeability measurements for the transcellular biomarker EBA and small hydrophilic paracellular reference molecule fluorescein